Diffinity RapidTip2 for PCR Purification with Polymerase Removal

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Diffinity RapidTip2 User Handbook

Diffinity RapidTip2 for PCR Purification with Polymerase Removal

• One Minute PCR purification
• Effectively removes dNTPs, primers, primer-dimers, and DNA polymerase
• High purity and yield
• Use in downstream applications such as restriction digest, T-A cloning, and pre-Sanger sequencing reactions
• Purifies a 50ul post-PCR sample

The new Diffinity RapidTip2 functional pipette tip contains proprietary Diffinity technology that enables fast, effective purification of PCR samples in one minute, in one step using just our RapidTip2 tip and a pipettor!

In just one simple mixing step, the RapidTip2 binds the impurities in a PCR reaction while leaving just the purified amplicon in solution.  DNA polymerase is removed to undetectable levels along with up to 90% of dNTPs, primers, and primers-dimers which bind to the technology inside of the tip.

The RapidTip2 is different than the original RapidTip for PCR purification (Pre-Sanger Sequencing) in that it's optimized for a 50ul PCR sample volume and has been tested to additionally remove standard, hot start, and proofreading DNA polymerases. 

The RapidTip2 is easy to use and environmentally friendly, too.  Everything you need to purify your PCR sample is contained in the tip - no additional reagents, consumables, or energy consuming capital equipment is needed.  When you're done with your purification, just toss the tip in regular lab trash.

LTS is a registered trademark of Rainin Instrument, LLC.